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Phosphorylated Intrinsically Disordered Region of FACT Masks Its Nucleosomal DNA Binding Elements
FACT is a heterodimer of SPT16 and SSRP1, which each contain several conserved regions in the primary structure. The interaction of FACT with nucleosomes induces chromatin remodeling through the combinatorial action of its distinct functional protein regions. However, there is little mechanistic ins...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782050/ https://ncbi.nlm.nih.gov/pubmed/19605348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001958 |
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