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Phosphorylated Intrinsically Disordered Region of FACT Masks Its Nucleosomal DNA Binding Elements

FACT is a heterodimer of SPT16 and SSRP1, which each contain several conserved regions in the primary structure. The interaction of FACT with nucleosomes induces chromatin remodeling through the combinatorial action of its distinct functional protein regions. However, there is little mechanistic ins...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tsunaka, Yasuo, Toga, Junko, Yamaguchi, Hiroto, Tate, Shin-ichi, Hirose, Susumu, Morikawa, Kosuke
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782050/
https://ncbi.nlm.nih.gov/pubmed/19605348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001958
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