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Phosphorylated Intrinsically Disordered Region of FACT Masks Its Nucleosomal DNA Binding Elements

FACT is a heterodimer of SPT16 and SSRP1, which each contain several conserved regions in the primary structure. The interaction of FACT with nucleosomes induces chromatin remodeling through the combinatorial action of its distinct functional protein regions. However, there is little mechanistic ins...

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מידע ביבליוגרפי
Main Authors: Tsunaka, Yasuo, Toga, Junko, Yamaguchi, Hiroto, Tate, Shin-ichi, Hirose, Susumu, Morikawa, Kosuke
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782050/
https://ncbi.nlm.nih.gov/pubmed/19605348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001958
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