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Asparagine-linked Oligosaccharides Present on a Non-consensus Amino Acid Sequence in the C(H)1 Domain of Human Antibodies

We report that N-linked oligosaccharide structures can be present on an asparagine residue not adhering to the consensus site motif NX(S/T), where X is not proline, described in the literature. We have observed oligosaccharides on a non-consensus asparaginyl residue in the C(H)1 constant domain of I...

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Detalhes bibliográficos
Main Authors: Valliere-Douglass, John F., Kodama, Paul, Mujacic, Mirna, Brady, Lowell J., Wang, Wes, Wallace, Alison, Yan, Boxu, Reddy, Pranhitha, Treuheit, Michael J., Balland, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781664/
https://ncbi.nlm.nih.gov/pubmed/19767389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014803
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