The Dexamethasone-induced Inhibition of Proliferation, Migration, and Invasion in Glioma Cell Lines Is Antagonized by Macrophage Migration Inhibitory Factor (MIF) and Can Be Enhanced by Specific MIF Inhibitors

Glioblastomas (GBMs) are the most frequent and malignant brain tumors in adults. Glucocorticoids (GCs) are routinely used in the treatment of GBMs for their capacity to reduce the tumor-associated edema. Few in vitro studies have suggested that GCs inhibit the migration and invasion of GBM cells thr...

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Hlavní autoři: Piette, Caroline, Deprez, Manuel, Roger, Thierry, Noël, Agnès, Foidart, Jean-Michel, Munaut, Carine
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781663/
https://ncbi.nlm.nih.gov/pubmed/19759012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014589
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