The Dexamethasone-induced Inhibition of Proliferation, Migration, and Invasion in Glioma Cell Lines Is Antagonized by Macrophage Migration Inhibitory Factor (MIF) and Can Be Enhanced by Specific MIF Inhibitors

Glioblastomas (GBMs) are the most frequent and malignant brain tumors in adults. Glucocorticoids (GCs) are routinely used in the treatment of GBMs for their capacity to reduce the tumor-associated edema. Few in vitro studies have suggested that GCs inhibit the migration and invasion of GBM cells thr...

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Detalhes bibliográficos
Main Authors: Piette, Caroline, Deprez, Manuel, Roger, Thierry, Noël, Agnès, Foidart, Jean-Michel, Munaut, Carine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781663/
https://ncbi.nlm.nih.gov/pubmed/19759012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014589
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