Direct Modification of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor by Dietary Isothiocyanates

Isothiocyanates are a class of phytochemicals with widely reported anti-cancer and anti-inflammatory activity. However, knowledge of their activity at a molecular level is limited. The objective of this study was to identify biological targets of phenethyl isothiocyanate (PEITC) using an affinity pu...

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Autori principali: Brown, Kristin K., Blaikie, Frances H., Smith, Robin A. J., Tyndall, Joel D. A., Lue, Hongqi, Bernhagen, Jürgen, Winterbourn, Christine C., Hampton, Mark B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Protein Synthesis, Post-Translational Modification, and Degradation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781657/
https://ncbi.nlm.nih.gov/pubmed/19776019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047092
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