Rho Family GTPase Modification and Dependence on CAAX Motif-signaled Posttranslational Modification

Rho GTPases (20 human members) comprise a major branch of the Ras superfamily of small GTPases, and aberrant Rho GTPase function has been implicated in oncogenesis and other human diseases. Although many of our current concepts of Rho GTPases are based on the three classical members (RhoA, Rac1, and...

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Hauptverfasser: Roberts, Patrick J., Mitin, Natalia, Keller, Patricia J., Chenette, Emily J., Madigan, James P., Currin, Rachel O., Cox, Adrienne D., Wilson, Oswald, Kirschmeier, Paul, Der, Channing J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533093/
https://ncbi.nlm.nih.gov/pubmed/18614539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800882200
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