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Rho Family GTPase Modification and Dependence on CAAX Motif-signaled Posttranslational Modification
Rho GTPases (20 human members) comprise a major branch of the Ras superfamily of small GTPases, and aberrant Rho GTPase function has been implicated in oncogenesis and other human diseases. Although many of our current concepts of Rho GTPases are based on the three classical members (RhoA, Rac1, and...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533093/ https://ncbi.nlm.nih.gov/pubmed/18614539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800882200 |
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