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Suppression of Long Chain Acyl-CoA Synthetase 3 Decreases Hepatic de Novo Fatty Acid Synthesis through Decreased Transcriptional Activity

Long chain acyl-CoA synthetases (ACSL) and fatty acid transport proteins (FATP) activate fatty acids to acyl-CoAs in the initial step of fatty acid metabolism. Numerous isoforms of ACSL and FATP exist with different tissue distribution patterns, intracellular locations, and substrate preferences, su...

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Detalhes bibliográficos
Main Authors: Bu, So Young, Mashek, Mara T., Mashek, Douglas G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781602/
https://ncbi.nlm.nih.gov/pubmed/19737935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036665
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