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Direct Fe(2+) Sensing by Iron-responsive Messenger RNA·Repressor Complexes Weakens Binding

Fe(2+) is now shown to weaken binding between ferritin and mitochondrial aconitase messenger RNA noncoding regulatory structures ((iron-responsive element) (IRE)-RNAs) and the regulatory proteins (IRPs), which adds a direct role of iron to regulation that can complement the well known regulatory pro...

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Détails bibliographiques
Auteurs principaux: Khan, Mateen A., Walden, William E., Goss, Dixie J., Theil, Elizabeth C.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781567/
https://ncbi.nlm.nih.gov/pubmed/19720833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041061
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