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Distinct Amino Termini of Two Human HCS Isoforms Influence Biotin Acceptor Substrate Recognition

The human holocarboxylase synthetase (HCS) catalyzes transfer of biotin to biotin-dependent carboxylases, and the enzyme is therefore of fundamental importance for many physiological processes, including fatty acid synthesis, gluconeogenesis, and amino acid catabolism. In addition, the enzyme functi...

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Detalhes bibliográficos
Main Authors: Ingaramo, Maria, Beckett, Dorothy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781485/
https://ncbi.nlm.nih.gov/pubmed/19740736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046201
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