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Distinct Amino Termini of Two Human HCS Isoforms Influence Biotin Acceptor Substrate Recognition
The human holocarboxylase synthetase (HCS) catalyzes transfer of biotin to biotin-dependent carboxylases, and the enzyme is therefore of fundamental importance for many physiological processes, including fatty acid synthesis, gluconeogenesis, and amino acid catabolism. In addition, the enzyme functi...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781485/ https://ncbi.nlm.nih.gov/pubmed/19740736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046201 |
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