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Selectivity in Post-translational Biotin Addition to Five Human Carboxylases
Human holocarboxylase synthetase (HCS) catalyzes linkage of the vitamin biotin to the biotin carboxyl carrier protein (BCCP) domain of five biotin-dependent carboxylases. In the two-step reaction, the activated intermediate, bio-5′-AMP, is first synthesized from biotin and ATP, followed by covalent...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265863/ https://ncbi.nlm.nih.gov/pubmed/22123817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.275982 |
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