Crosstalk between Protease-activated Receptor 1 and Platelet-activating Factor Receptor Regulates Melanoma Cell Adhesion Molecule (MCAM/MUC18) Expression and Melanoma Metastasis

The cellular and molecular pathways that regulate platelet activation, blood coagulation, and inflammation are emerging as critical players in cancer progression and metastasis. Here, we demonstrate a novel signaling mechanism whereby protease-activated receptor 1 (PAR1) mediates expression of melan...

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Detalles Bibliográficos
Main Authors: Melnikova, Vladislava O., Balasubramanian, Krishnakumar, Villares, Gabriel J., Dobroff, Andrey S., Zigler, Maya, Wang, Hua, Petersson, Frederik, Price, Janet E., Schroit, Alan, Prieto, Victor G., Hung, Mien-Chie, Bar-Eli, Menashe
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781430/
https://ncbi.nlm.nih.gov/pubmed/19703903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.042150
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