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Novel Regulatory Site within the TM3–4 Loop of Human Recombinant α3 Glycine Receptors Determines Channel Gating and Domain Structure
Glycine receptors are Cys loop ligand-gated ion channels that mediate fast inhibitory synaptic transmission in the mammalian central nervous system. The functionally distinct splice variants α3L and α3K of the human glycine receptor differ by a 15-amino acid insert within the long intracellular TM3–...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781406/ https://ncbi.nlm.nih.gov/pubmed/19661067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043174 |
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