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Localized Diacylglycerol-dependent Stimulation of Ras and Rap1 during Phagocytosis

We describe a role for diacylglycerol in the activation of Ras and Rap1 at the phagosomal membrane. During phagocytosis, Ras density was similar on the surface and invaginating areas of the membrane, but activation was detectable only in the latter and in sealed phagosomes. Ras activation was associ...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Botelho, Roberto J., Harrison, Rene E., Stone, James C., Hancock, John F., Philips, Mark R., Jongstra-Bilen, Jenny, Mason, David, Plumb, Jonathan, Gold, Michael R., Grinstein, Sergio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781395/
https://ncbi.nlm.nih.gov/pubmed/19700408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009514
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