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Rac1 promotes TGF-β-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism
Transforming growth factor (TGF)-β is a central mediator in the progression of glomerulosclerosis, leading to accumulation of aberrant extracellular matrix proteins and inappropriate expression of smooth muscle α-actin in the kidney. Previously, we reported that disrupting the cytoskeleton diminishe...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Physiological Society
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781339/ https://ncbi.nlm.nih.gov/pubmed/19726546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00345.2009 |
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