LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse

Liver X receptors (LXRs) are ligand-activated transcription factors that coordinate regulation of gene expression involved in several cellular functions but most notably cholesterol homeostasis encompassing cholesterol transport, catabolism, and absorption. WAY-252623 (LXR-623) is a highly selective...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Quinet, Elaine M., Basso, Michael D., Halpern, Anita R., Yates, David W., Steffan, Robert J., Clerin, Valerie, Resmini, Christine, Keith, James C., Berrodin, Thomas J., Feingold, Irene, Zhong, Wenyan, Hartman, Helen B., Evans, Mark J., Gardell, Stephen J., DiBlasio-Smith, Elizabeth, Mounts, William M., LaVallie, Edward R., Wrobel, Jay, Nambi, Ponnal, Vlasuk, George P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781308/
https://ncbi.nlm.nih.gov/pubmed/19318684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900037-JLR200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados