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Integrative Discovery of Epigenetically Derepressed Cancer Testis Antigens in NSCLC

BACKGROUND: Cancer/testis antigens (CTAs) were first discovered as immunogenic targets normally expressed in germline cells, but differentially expressed in a variety of human cancers. In this study, we used an integrative epigenetic screening approach to identify coordinately expressed genes in hum...

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Главные авторы: Glazer, Chad A., Smith, Ian M., Ochs, Michael F., Begum, Shahnaz, Westra, William, Chang, Steven S., Sun, Wenyue, Bhan, Sheetal, Khan, Zubair, Ahrendt, Steven, Califano, Joseph A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781168/
https://ncbi.nlm.nih.gov/pubmed/19997593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008189
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