Combined Anti-Angiogenic Therapy Targeting PDGF and VEGF Receptors Lowers the Interstitial Fluid Pressure in a Murine Experimental Carcinoma

Elevation of the interstitial fluid pressure (IFP) of carcinoma is an obstacle in treatment of tumors by chemotherapy and correlates with poor drug uptake. Previous studies have shown that treatment with inhibitors of platelet-derived growth factor (PDGF) or vascular endothelial growth factor (VEGF)...

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Hlavní autoři: Kłosowska-Wardęga, Agnieszka, Hasumi, Yoko, Burmakin, Mikhail, Åhgren, Aive, Stuhr, Linda, Moen, Ingrid, Reed, Rolf K., Rubin, Kristofer, Hellberg, Carina, Heldin, Carl-Henrik
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781164/
https://ncbi.nlm.nih.gov/pubmed/19997591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008149
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