Increased Fibrosis and Interstitial Fluid Pressure in Two Different Types of Syngeneic Murine Carcinoma Grown in Integrin β3-Subunit Deficient Mice

Stroma properties affect carcinoma physiology and direct malignant cell development. Here we present data showing that α(V)β(3) expressed by stromal cells is involved in the control of interstitial fluid pressure (IFP), extracellular volume (ECV) and collagen scaffold architecture in experimental mu...

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Detalhes bibliográficos
Main Authors: Friman, Tomas, Gustafsson, Renata, Stuhr, Linda B., Chidiac, Jean, Heldin, Nils-Erik, Reed, Rolf K., Oldberg, Åke, Rubin, Kristofer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316610/
https://ncbi.nlm.nih.gov/pubmed/22479530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034082
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