Increased Fibrosis and Interstitial Fluid Pressure in Two Different Types of Syngeneic Murine Carcinoma Grown in Integrin β3-Subunit Deficient Mice

Stroma properties affect carcinoma physiology and direct malignant cell development. Here we present data showing that α(V)β(3) expressed by stromal cells is involved in the control of interstitial fluid pressure (IFP), extracellular volume (ECV) and collagen scaffold architecture in experimental mu...

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Autors principals: Friman, Tomas, Gustafsson, Renata, Stuhr, Linda B., Chidiac, Jean, Heldin, Nils-Erik, Reed, Rolf K., Oldberg, Åke, Rubin, Kristofer
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316610/
https://ncbi.nlm.nih.gov/pubmed/22479530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034082
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