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Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma
BACKGROUND: Imatinib causes increased turnover of stromal collagen, reduces collagen fibril diameter, enhances extracellular fluid turnover and lowers interstitial fluid pressure (IFP) in the human colonic carcinoma KAT-4/HT-29 (KAT-4) xenograft model. METHODS: We compared the effects of imatinib on...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324310/ https://ncbi.nlm.nih.gov/pubmed/28231806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1142-7 |
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