Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy antigen receptor for chemokines

We reported that PARP-1 exhibits differential roles in expression of inflammatory factors. Here, we show that PARP-1 deletion was associated with a significant reduction in inflammatory cell recruitment to mouse airways upon intratracheal administration of LPS. However, PARP-1 deletion exerted littl...

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Bibliographische Detailangaben
Hauptverfasser: Zerfaoui, Mourad, Naura, Amarjit S., Errami, Youssef, Hans, Chetan P., Rezk, Bashir M., Park, Jiwon, Elsegeiny, Waleed, Kim, Hogyoung, Lord, Kevin, Kim, Jong G., Boulares, A. Hamid
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Leukocyte Biology 2009
Schlagworte:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780916/
https://ncbi.nlm.nih.gov/pubmed/19741160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0309183
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