Endoplasmic Reticulum Stress in Diabetic Hearts Abolishes Erythropoietin-Induced Myocardial Protection by Impairment of Phospho–Glycogen Synthase Kinase-3β–Mediated Suppression of Mitochondrial Permeability Transition

OBJECTIVE: Alteration in endoplasmic reticulum (ER) stress in diabetic hearts and its effect on cytoprotective signaling are unclear. Here, we examine the hypothesis that ER stress in diabetic hearts impairs phospho–glycogen synthase kinase (GSK)-3β–mediated suppression of mitochondrial permeability...

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Bibliografiske detaljer
Main Authors: Miki, Takayuki, Miura, Tetsuji, Hotta, Hiroyuki, Tanno, Masaya, Yano, Toshiyuki, Sato, Takahiro, Terashima, Yoshiaki, Takada, Akifumi, Ishikawa, Satoko, Shimamoto, Kazuaki
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2009
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780889/
https://ncbi.nlm.nih.gov/pubmed/19755525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0158
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