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Endoplasmic Reticulum Stress in Diabetic Hearts Abolishes Erythropoietin-Induced Myocardial Protection by Impairment of Phospho–Glycogen Synthase Kinase-3β–Mediated Suppression of Mitochondrial Permeability Transition

OBJECTIVE: Alteration in endoplasmic reticulum (ER) stress in diabetic hearts and its effect on cytoprotective signaling are unclear. Here, we examine the hypothesis that ER stress in diabetic hearts impairs phospho–glycogen synthase kinase (GSK)-3β–mediated suppression of mitochondrial permeability...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Miki, Takayuki, Miura, Tetsuji, Hotta, Hiroyuki, Tanno, Masaya, Yano, Toshiyuki, Sato, Takahiro, Terashima, Yoshiaki, Takada, Akifumi, Ishikawa, Satoko, Shimamoto, Kazuaki
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Diabetes Association 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780889/
https://ncbi.nlm.nih.gov/pubmed/19755525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0158
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