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A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion

The influential role of Wnt5a in tumor progression underscores the requirement for developing molecules that can target Wnt5a-mediated cellular responses. In the aggressive skin cancer, melanoma, elevated Wnt5a expression promotes cell motility and drives metastasis. Two approaches can be used to co...

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書誌詳細
主要な著者: Jenei, Veronika, Sherwood, Victoria, Howlin, Jillian, Linnskog, Rickard, Säfholm, Annette, Axelsson, Lena, Andersson, Tommy
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780806/
https://ncbi.nlm.nih.gov/pubmed/19901340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909409106
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