WNT‐5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells

An important role for WNT‐5A is implicated in a variety of tumors, including breast carcinoma. We previously showed that WNT‐5A signaling inhibits migration and metastasis of breast cancer cells, and that patients with primary breast cancer in which WNT‐5A was expressed have a better prognosis. Desp...

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Publicat a:Mol Oncol
Autors principals: Prasad, Chandra Prakash, Chaurasiya, Shivendra Kumar, Axelsson, Lena, Andersson, Tommy
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528454/
https://ncbi.nlm.nih.gov/pubmed/23727359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.04.005
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