Demonstration of a WNT5A-IL-6 positive feedback loop in melanoma cells: Dual interference of this loop more effectively impairs melanoma cell invasion

Increased expression and signalling of WNT5A and interleukin-6 (IL-6) have both been shown to promote melanoma progression. Here, we investigated the proposed existence of a WNT5A-IL-6 positive feedback loop that drives melanoma migration and invasion. First, the HOPP algorithm revealed that the inv...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Linnskog, Rickard, Mohapatra, Purusottam, Moradi, Farnaz, Prasad, Chandra Prakash, Andersson, Tommy
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122349/
https://ncbi.nlm.nih.gov/pubmed/27191257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9332
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