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Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini

Proteolysis has major roles in diverse biologic processes and regulates the activity, localization, and intracellular levels of proteins. Linking signaling pathways and physiologic processes to specific proteolytic processing events is a major challenge in signal transduction research. Here, we desc...

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Bibliografiske detaljer
Main Authors: Xu, Guoqiang, Shin, Sung Bin Y., Jaffrey, Samie R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780798/
https://ncbi.nlm.nih.gov/pubmed/19892738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908958106
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