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Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini

Proteolysis has major roles in diverse biologic processes and regulates the activity, localization, and intracellular levels of proteins. Linking signaling pathways and physiologic processes to specific proteolytic processing events is a major challenge in signal transduction research. Here, we desc...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Xu, Guoqiang, Shin, Sung Bin Y., Jaffrey, Samie R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780798/
https://ncbi.nlm.nih.gov/pubmed/19892738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908958106
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