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Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini

Proteolysis has major roles in diverse biologic processes and regulates the activity, localization, and intracellular levels of proteins. Linking signaling pathways and physiologic processes to specific proteolytic processing events is a major challenge in signal transduction research. Here, we desc...

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Autors principals: Xu, Guoqiang, Shin, Sung Bin Y., Jaffrey, Samie R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780798/
https://ncbi.nlm.nih.gov/pubmed/19892738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908958106
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