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G9a selectively represses a class of late-replicating genes at the nuclear periphery
We have investigated the role of the histone methyltransferase G9a in the establishment of silent nuclear compartments. Following conditional knockout of the G9a methyltransferase in mouse ESCs, 167 genes were significantly up-regulated, and no genes were strongly down-regulated. A partially overlap...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2780741/ https://ncbi.nlm.nih.gov/pubmed/19889976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906142106 |
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