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G9a selectively represses a class of late-replicating genes at the nuclear periphery
We have investigated the role of the histone methyltransferase G9a in the establishment of silent nuclear compartments. Following conditional knockout of the G9a methyltransferase in mouse ESCs, 167 genes were significantly up-regulated, and no genes were strongly down-regulated. A partially overlap...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2780741/ https://ncbi.nlm.nih.gov/pubmed/19889976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906142106 |
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