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How Many Genetic Variants Remain to Be Discovered?
A great majority of genetic markers discovered in recent genome-wide association studies have small effect sizes, and they explain only a small fraction of the genetic contribution to the diseases. How many more variants can we expect to discover and what study sizes are needed? We derive the connec...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2780697/ https://ncbi.nlm.nih.gov/pubmed/19956539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007969 |
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