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Strategies and issues in the detection of pathway enrichment in genome-wide association studies

A fundamental question in human genetics is the degree to which the polygenic character of complex traits derives from polymorphism in genes with similar or with dissimilar functions. The many genome-wide association studies now being performed offer an opportunity to investigate this, and although...

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Detalhes bibliográficos
Main Authors: Hong, Mun-Gwan, Pawitan, Yudi, Magnusson, Patrik K.E., Prince, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865249/
https://ncbi.nlm.nih.gov/pubmed/19408013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-009-0676-z
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