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Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease

Genome-wide association studies (GWAS) that allow for allelic heterogeneity may facilitate the discovery of novel genes not detectable by models that require replication of a single variant site. One strategy to accomplish this is to focus on genes rather than markers as units of association, and so...

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Hlavní autoři: Hong, Mun-Gwan, Reynolds, Chandra A., Feldman, Adina L., Kallin, Mikael, Lambert, Jean-Charles, Amouyel, Philippe, Ingelsson, Erik, Pedersen, Nancy L., Prince, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326347/
https://ncbi.nlm.nih.gov/pubmed/22190428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22009
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