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Delayed onset of the diurnal melatonin rise in patients with Huntington’s disease

Sleep disturbances are very prevalent in Huntington’s disease (HD) patients and can substantially impair their quality of life. Accumulating evidence suggests considerable dysfunction of the hypothalamic suprachiasmatic nucleus (SCN), the biological clock, in both HD patients and transgenic mouse mo...

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Dettagli Bibliografici
Autori principali: Aziz, N. Ahmad, Pijl, Hanno, Frölich, Marijke, Schröder-van der Elst, Janny P., van der Bent, Chris, Roelfsema, Ferdinand, Roos, Raymund A. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: D. Steinkopff-Verlag 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780627/
https://ncbi.nlm.nih.gov/pubmed/19562249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-009-5196-1
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