Delayed onset of the diurnal melatonin rise in patients with Huntington’s disease

Sleep disturbances are very prevalent in Huntington’s disease (HD) patients and can substantially impair their quality of life. Accumulating evidence suggests considerable dysfunction of the hypothalamic suprachiasmatic nucleus (SCN), the biological clock, in both HD patients and transgenic mouse mo...

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Detalhes bibliográficos
Main Authors: Aziz, N. Ahmad, Pijl, Hanno, Frölich, Marijke, Schröder-van der Elst, Janny P., van der Bent, Chris, Roelfsema, Ferdinand, Roos, Raymund A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: D. Steinkopff-Verlag 2009
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780627/
https://ncbi.nlm.nih.gov/pubmed/19562249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-009-5196-1
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