Purification and Characterization of the Epoxidase Catalyzing the Formation of Fosfomycin from Pseudomonas syringae

The final step in the biosynthesis of fosfomycin in Streptomyces wedmorensis is catalyzed by (S)-2-hydroxypropylphosphonic acid (HPP) epoxidase (Sw-HppE). A homologous enzyme from Pseudomonas syringae has recently been isolated whose encoding gene (orf3) shares relatively low sequence homology to th...

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Hlavní autoři: Munos, Jeffrey W., Moon, Sung-Ju, Mansoorabadi, Steven O., Chang, Weichen, Hong, Lin, Yan, Feng, Liu, Aimin, Liu, Hung-wen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780581/
https://ncbi.nlm.nih.gov/pubmed/18656958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800877v
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