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A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity

BACKGROUND: Based on its role in angiogenesis and apoptosis, the inhibition of NFκB activity is considered an effective treatment for cancer, hampered by the lack of selective and safe inhibitors. We recently demonstrated that the RH domain of GRK5 (GRK5-RH) inhibits NFκB, thus we evaluated its effe...

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Hlavní autoři: Sorriento, Daniela, Campanile, Alfonso, Santulli, Gaetano, Leggiero, Eleonora, Pastore, Lucio, Trimarco, Bruno, Iaccarino, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780391/
https://ncbi.nlm.nih.gov/pubmed/19900276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-97
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