A Novel Small Peptide Inhibitor of NFκB, RH10, Blocks Oxidative Stress-Dependent Phenotypes in Cancer

BACKGROUND: The RH domain of GRK5 is an effective modulator of cancer growth through the inhibition of NFκB activity. The aim of this study was to identify the minimum effective sequence of RH that is still able to inhibit tumor growth and could be used as a peptide-based drug for therapy. METHODS:...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Gambardella, Jessica, Ciccarelli, Michele, Del Giudice, Carmine, Fiordelisi, Antonella, De Rosa, Matteo, Sala, Marina, Pacelli, Roberto, Campiglia, Pietro, Trimarco, Bruno, Iaccarino, Guido, Sorriento, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247396/
https://ncbi.nlm.nih.gov/pubmed/30524659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5801807
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