Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain

BACKGROUND: We previously reported that intrathecal injection of lysophosphatidylcholine (LPC) induced neuropathic pain through activation of the lysophosphatidic acid (LPA)-1 receptor, possibly via conversion to LPA by autotaxin (ATX). RESULTS: We examined in vivo LPA-induced LPA production using a...

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Bibliographische Detailangaben
Hauptverfasser: Ma, Lin, Uchida, Hitoshi, Nagai, Jun, Inoue, Makoto, Chun, Jerold, Aoki, Junken, Ueda, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780384/
https://ncbi.nlm.nih.gov/pubmed/19912636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-64
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