Disruption of cAMP and Prostaglandin E(2) Transport by Multidrug Resistance Protein 4 Deficiency Alters cAMP-Mediated Signaling and Nociceptive Response

Multidrug resistance protein 4 (MRP4; ABCC4) is a member of the MRP/ATP-binding cassette family serving as a transmembrane transporter involved in energy-dependent efflux of anticancer/antiviral nucleotide agents and of physiological substrates, including cyclic nucleotides and prostaglandins (PGs)....

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Detalhes bibliográficos
Main Authors: Lin, Z. Ping, Zhu, Yong-Lian, Johnson, Dennis R., Rice, Kevin P., Nottoli, Timothy, Hains, Bryan C., McGrath, James, Waxman, Stephen G., Sartorelli, Alan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780335/
https://ncbi.nlm.nih.gov/pubmed/17959714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.039594
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