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Disruption of Dictyostelium discoideum morphogenesis by overproduction of cAMP phosphodiesterase.

The development and cellular differentiation of Dictyostelium discoideum are disrupted in transformants secreting high levels of the cyclic nucleotide phosphodiesterase. The aggregation of these cells in the early stage of development proceeds rapidly and without the formation of organized streams....

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Faure, M, Podgorski, G J, Franke, J, Kessin, R H
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2847151/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8076
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