Disruption of Dictyostelium discoideum morphogenesis by overproduction of cAMP phosphodiesterase.
The development and cellular differentiation of Dictyostelium discoideum are disrupted in transformants secreting high levels of the cyclic nucleotide phosphodiesterase. The aggregation of these cells in the early stage of development proceeds rapidly and without the formation of organized streams....
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2847151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.21.8076 |
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