High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo

BACKGROUND: The strong association between aberrant HDAC activity and the occurrence of cancer has led to the development of a variety of HDAC inhibitors (HDIs), which emerge as promising new targeted anticancer therapeutics. METHODS: Due to the pivotal role of RelA/p65 in the tumorigenesis of pancr...

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Main Authors: Lehmann, Annika, Denkert, Carsten, Budczies, Jan, Buckendahl, Ann-Christin, Darb-Esfahani, Silvia, Noske, Aurelia, Müller, Berit Maria, Bahra, Marcus, Neuhaus, Peter, Dietel, Manfred, Kristiansen, Glen, Weichert, Wilko
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779818/
https://ncbi.nlm.nih.gov/pubmed/19912635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-395
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