Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes

BACKGROUND: Integrase inhibitors are currently being incorporated into highly active antiretroviral therapy (HAART). Due to high HIV variability, integrase inhibitor efficacy must be evaluated against a range of integrase enzymes from different subtypes. METHODS: This study compares the enzymatic ac...

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Detalhes bibliográficos
Main Authors: Bar-Magen, Tamara, Sloan, Richard D, Faltenbacher, Verena H, Donahue, Daniel A, Kuhl, Björn D, Oliveira, Maureen, Xu, Hongtao, Wainberg, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779801/
https://ncbi.nlm.nih.gov/pubmed/19906306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-103
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