Tetherin restricts direct cell-to-cell infection of HIV-1

BACKGROUND: Tetherin (BST-2/CD317/HM1.24) is an interferon (IFN)-inducible factor of the innate immune system, recently shown to exert antiviral activity against HIV-1 and other enveloped viruses by tethering nascent viral particles to the cell surface, thereby inhibiting viral release. In HIV-1 inf...

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Bibliographic Details
Main Authors: Kuhl, Björn D, Sloan, Richard D, Donahue, Daniel A, Bar-Magen, Tamara, Liang, Chen, Wainberg, Mark A
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017029/
https://ncbi.nlm.nih.gov/pubmed/21184674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-115
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