Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells

The histone H3 Lys 9 (H3K9) methyltransferase Eset is an epigenetic regulator critical for the development of the inner cell mass (ICM). Although ICM-derived embryonic stem (ES) cells are normally unable to contribute to the trophectoderm (TE) in blastocysts, we find that depletion of Eset by shRNAs...

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Detalhes bibliográficos
Main Authors: Yuan, Ping, Han, Jianyong, Guo, Guoji, Orlov, Yuriy L., Huss, Mikael, Loh, Yuin-Han, Yaw, Lai-Ping, Robson, Paul, Lim, Bing, Ng, Huck-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779752/
https://ncbi.nlm.nih.gov/pubmed/19884257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1831909
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