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Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
The histone H3 Lys 9 (H3K9) methyltransferase Eset is an epigenetic regulator critical for the development of the inner cell mass (ICM). Although ICM-derived embryonic stem (ES) cells are normally unable to contribute to the trophectoderm (TE) in blastocysts, we find that depletion of Eset by shRNAs...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779752/ https://ncbi.nlm.nih.gov/pubmed/19884257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1831909 |
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