The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation

The first cellular differentiation event in mouse development leads to the formation of the blastocyst consisting of the inner cell mass (ICM) and trophectoderm (TE). The transcription factor CDX2 is required for proper TE specification, where it promotes expression of TE genes, and represses expres...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Daosheng, Guo, Guoji, Yuan, Ping, Ralston, Amy, Sun, Lingang, Huss, Mikael, Mistri, Tapan, Pinello, Luca, Ng, Huck Hui, Yuan, Guocheng, Ji, Junfeng, Rossant, Janet, Robson, Paul, Han, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719399/
https://ncbi.nlm.nih.gov/pubmed/29214996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16009-w
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