Genome Wide Analysis of Chromatin Regulation by Cocaine Reveals a Novel Role for Sirtuins

Changes in gene expression contribute to the long-lasting regulation of the brain’s reward circuitry seen in drug addiction, however, the specific genes regulated and the transcriptional mechanisms underlying such regulation remain poorly understood. Here, we used chromatin immunoprecipitation coupl...

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Autori principali: Renthal, William, Kumar, Arvind, Xiao, Guanghua, Wilkinson, Matthew, Covington, Herbert E., Maze, Ian, Sikder, Devanjan, Robison, Alfred J., LaPlant, Quincey, Dietz, David M., Russo, Scott J., Vialou, Vincent, Chakravarty, Sumana, Kodadek, Thomas J., Stack, Ashley, Kabbaj, Mohammed, Nestler, Eric J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779727/
https://ncbi.nlm.nih.gov/pubmed/19447090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.03.026
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