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ΔFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine

The effects of addictive drugs change with repeated use: many individuals become tolerant of their pleasurable effects but also more sensitive to negative sequelae (e.g., anxiety, paranoia, and drug craving). Understanding the mechanisms underlying such tolerance and sensitization may provide valuab...

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書誌詳細
主要な著者: Winstanley, Catharine A., Green, Thomas A., Theobald, David E.H., Renthal, William, LaPlant, Quincey, DiLeone, Ralph J., Chakravarty, Sumana, Nestler, Eric J.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820241/
https://ncbi.nlm.nih.gov/pubmed/19135469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.12.007
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