ΔFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine

The effects of addictive drugs change with repeated use: many individuals become tolerant of their pleasurable effects but also more sensitive to negative sequelae (e.g., anxiety, paranoia, and drug craving). Understanding the mechanisms underlying such tolerance and sensitization may provide valuab...

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Hlavní autoři: Winstanley, Catharine A., Green, Thomas A., Theobald, David E.H., Renthal, William, LaPlant, Quincey, DiLeone, Ralph J., Chakravarty, Sumana, Nestler, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820241/
https://ncbi.nlm.nih.gov/pubmed/19135469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.12.007
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