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ΔFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine

The effects of addictive drugs change with repeated use: many individuals become tolerant of their pleasurable effects but also more sensitive to negative sequelae (e.g., anxiety, paranoia, and drug craving). Understanding the mechanisms underlying such tolerance and sensitization may provide valuab...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Winstanley, Catharine A., Green, Thomas A., Theobald, David E.H., Renthal, William, LaPlant, Quincey, DiLeone, Ralph J., Chakravarty, Sumana, Nestler, Eric J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820241/
https://ncbi.nlm.nih.gov/pubmed/19135469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.12.007
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